Gene information
Official symbol GGT1
Official full name gamma-glutamyltransferase 1
Gene type protein-coding gene
Chromosome22q11.23
Alias symbolD22S672; D22S732; CD224
Previous symbolGGT
Gene familyCD molecules; Gamma-glutamyltransferases
Resources
Entrez Gene 2678
HGNC HGNC:4250
Ensembl ENSG00000100031
Vega OTTHUMG00000030859
UCSC uc003aan.2
GO terms: 14 records
GO Description Category LogP Number of genes Detail
GO:0006575 cellular modified amino acid metabolic process GO Biological Processes -7.43961662 26 More
GO:0007276 gamete generation GO Biological Processes -2.03816629 18 More
GO:0008233 peptidase activity GO Molecular Functions -21.0463733 46 More
GO:0009064 glutamine family amino acid metabolic process GO Biological Processes -4.49369376 12 More
GO:0016485 protein processing GO Biological Processes -23.0561441 30 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031638 zymogen activation GO Biological Processes -13.0866363 13 More
GO:0042398 cellular modified amino acid biosynthetic process GO Biological Processes -5.04832542 10 More
GO:0043171 peptide catabolic process GO Biological Processes -2.11862029 3 More
GO:0043648 dicarboxylic acid metabolic process GO Biological Processes -4.01197458 13 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0051604 protein maturation GO Biological Processes -20.0856790 31 More
GO:1901605 alpha-amino acid metabolic process GO Biological Processes -2.81275840 18 More
GO:1901607 alpha-amino acid biosynthetic process GO Biological Processes -2.12314076 8 More
Drug-Gene interaction
view
Related drugs: 18 records
Drug name Interaction type Source PMID View
adriamycin NCI 16871999 view
aminoglutethimide NCI 3427227 view
azacitidine NCI 9801800 view
cannabinol NCI 6140904 view
carbamazepine NCI 12402220 view
chembl1743358 NCI 1976855 view
dexamethasone NCI 2890444 view
diclofenac NCI 9090444 view
disulfiram NCI 8904971 view
ditiocarb NCI 6135240 view
gentamicin NCI 15736857 view
indomethacin NCI 9090444 view
liothyronine sodium NCI 7642172 view
mannitol NCI 11471882 view
mestranol NCI 6744303 view
phenytoin NCI 124022201346382 view
piroxicam NCI 9090444 view
tamoxifen NCI 2877750 view
Related studies: 6 records
Molecular factor Omics type Application Objective MI type Reference
glutathione hydrolase 1 proenzyme proteomics major adverse cardiovascular events[prognosis (bad)] ST elevation myocardial infarction Akpek M et al. Angiology. 2012
glutathione hydrolase 1 proenzyme proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Ozcan F et al. J Investig Med. 2012
glutathione hydrolase 1 proenzyme proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Ozcan F et al. J Investig Med. 2012
glutathione hydrolase 1 proenzyme proteomics no-reflow phenomenon[prognosis (bad)] acute ST elevation myocardial infarction Ozcan F et al. J Investig Med. 2012
glutathione hydrolase 1 proenzyme proteomics medium predictor cardiovascular death[prognosis (bad)] acute ST elevation myocardial infarction Gul M et al. Coron Artery Dis. 2013
glutathione hydrolase 1 proenzyme proteomics death[prognosis (bad)] acute myocardial infarction Kim JG et al. Medicine (Baltimore). 2018
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